

Treating osteoarthritis with Arthrosamid® is a safe and endogenous treatment for knee problems caused by osteoarthritis. Your body does not recognize the gel as something foreign, so there is no immune reaction. The gel stays securely in place in the knee joint and fuses with the joint capsule, the synovium. Because Arthrosamid® is not broken down or absorbed, it remains in the joint for a long time.
Arthrosamid® consists of 2.5% polyacrylamide hydrogel and 97.5% water. This hydrogel has been used for more than 25 years and more than 1,800,000 people worldwide have been treated with it. To date, no long-term or serious side effects have been observed.
If necessary, a knee replacement can still be placed later – even after treatment with Arthrosamid®.


Clinical research shows that after about 3 to 4 months, patients experience a marked reduction in pain, and can move better.
The effect can last up to 5 years after just one treatment.
Positive results are reported in 80% of cases.
In younger patients (under age 60), 9 out of 10 respond favorably.
In older patients (over 70 years old), this is the case in 6 to 7 in 10.


Arthrosamid® is injected into the joint gap of the knee. Once in the joint, it fuses with the capsule, making it more elastic and allowing you to move better and experience less pain .
Osteoarthritis is associated with recurrent inflammation in the joint, which causes pain and swelling. An injection of Arthrosamid® helps reduce this inflammation, so you experience noticeably fewer symptoms.
The big benefit? Reduced inflammation causes the joint capsule to start producing healthier joint fluid again. This improves the condition of your knee from the inside out – resulting in less pain, less swelling and better daily function.
Arthrosamid® is an innovative treatment with long-lasting results. The injectable hydrogel becomes a permanent part of the joint capsule. This makes the tissue more resilient and thicker. This helps reduce inflammation, pain and swelling and improves mobility.
Thanks to this integration, the quality of the synovial fluid also improves. Your knee moves more smoothly and is subjected to less stress. Arthrosamid® is not broken down or absorbed by the body, ensuring a long-term effect for up to 5 years after one treatment.
8 out of 10 patients experience marked improvement.
The treatment consists of one 6 ml injection under local anesthesia. After treatment, you may go home immediately. After a few days of rest, you can resume your daily activities.
Some people feel relief quickly thanks to the lubricating and shock-absorbing effect. For others, the effect occurs between 6 weeks and 4 months. Up to 6 months, you can expect improvement.
A healthy lifestyle and regular exercise have a positive effect on the final outcome.
Research shows that one injection can provide relief for up to 5 years. Therefore, Arthrosamid® is a safe and durable choice for those who want to address knee osteoarthritis without surgery.
Martine Somberg – “So the osteoarthritis remains, but now after six months my symptoms are just gone.”
Marcel Wolfert – “Several years ago I started having knee problems. The orthopedist diagnosed a tear in the meniscus and damage to the cartilage (osteoarthritis). Nothing to do and still too young for new knees. Advice: no more singles (tennis), no more skiing, no more sports. Now, eight weeks after Arthrosamid treatment, I can paddle twice a week and run 18 holes every weekend. The knees are doing well. They are a little sensitive a day after sports, but that quickly goes away.”
Jan Theunissen – After a long period of “knee trouble” due to severe osteoarthritis, I get the injection of Arthrosamid. Sport is important to me and for many years I thought that physical exercise was no longer possible because it would cause too much trouble in the knees. Now I can again teach (gym teacher), climb stairs, walk and ride a bike without any problems. I kept a journal about my experiences with Arthrosamid.
Sharron Davies – “my pain is probably reduced by about 80-85%. I can recommend treatment with Arthrosamid® to anyone with osteoarthritis of the knees.”
Arthrosamid® has proven to be a long-term and effective treatment for patients with knee osteoarthritis. Clinical studies show that 80% of treated patients experience significant improvement in pain reduction, mobility and function. These improvements are maintained for years after the initial injection (up to 5 years).

